Nature's Essentials Cinnamon 1000mg 120 Tablets

Anti-oxidant Activity Studies

Cinnamon bark contains procyanidins and catechins. The components of procyanidins include both procyanidin A-type and B-type linkages. These procyanidins extracted from cinnamon and berries also possess antioxidant activities.

The aqueous and alcoholic extract of cinnamon potentially significantly inhibits fatty acid oxidation and lipid peroxidation in vitro. Different flavonoids isolated from cinnamon have free-radical-scavenging activities and antioxidant properties. A study of the inhibitory effects of cinnamaldehyde and other compounds of cinnamon on nitric oxide production revealed that cinnamaldehyde possesses potential activity against the production of nitric oxide as well as the expression of inducible nitric oxide. The highest inhibitory activities were reported as 81.5%, 71.7%, and 41.2% at 1.0, 0.5, and 0.1 µg/µL, respectively. Lin et al. reported the in vivo antioxidant activity of two different extracts, the ethanolic and hot water extracts of the dry bark of C. cassia. The ethanolic extract of C. cassia exhibited significant inhibition (96.3%) compared to the natural antioxidant α-tocopherol (93.74%). Overall, cinnamon exhibited higher antioxidant activities compared to that of other dessert spices.

The essential oils and some of the major compounds present in cinnamon, including (E)-cinnamaldehyde, eugenol, and linalool, were investigated in reference to peroxynitrite-induced nitration and lipid peroxidation. Eugenol and the essential oils were more effective than the other two compounds. In a comparative study among 26 spices, cinnamon showed the highest antioxidant activity, indicating that it can be applied as an antioxidant used in foods. Another study investigated the effectiveness of a mixture of spices on oxidative stress markers as well as the antioxidant activity in high fructose-fed insulin-resistant rats. The mixture, which consisted of 1 g/100 g cinnamon bark, showed a significant antioxidant activity compared to the fructose alone group. Volatile oils from C. zeylanicum showed significant biological activities.